Dr. Cooke does both cellular and clinical research on how to keep our endothelium and thus our blood vessels throughout our body and brain healthy and elastic. In his clinic Dr. Cooke helps those with cardiovascular disease improve their health, strength and vitality.

His research is compelling, his suggestions are being used daily in his clinic, and the recipes are tasty and offer a useful start towards a healthier diet. Who knew argenine was important!

Peggy Henderson

The title of this book struck me as a bit of hyperbole, since most people think of "cure" in the sense of disease eradication. I guess that goal might be achieved in some cases by strict adherence to Dr. Cooke's guidelines, but I think the term the term "cure" in the title is better understood in the sense of "treatment for a disease". Dr. Cooke himself tells you that a clinically available test for endothelial dysfunction is still not available. It therefore seems premature to suggest that these guidelines have proven to be a real "cure" in the sense most people use that word. However, I certainly don't doubt those who say that following Dr. Cooke's advice has resulted in their feeling much better. In fact, I intend to try his two weeks of menus and diet guidelines to see if it helps me. I settled on a "four stars" for this book because first, most of the material in its 310 pages is a re-hash of information that's already available elsewhere - for example, the benefits of fruits and vegetables, fiber, soy, fish oil, various supplements, aerobic exercise; and the dangers of elevated homocystein or low HDL etc. These recommendations could be found in virtually any recent book or website aiming to educate people about preventing or treating heart disease,although Dr. Cooke (and Ms. Zimmer) do a good job of bringing these topics together and explaining how they help with one's endothelium. Second, the diet recommendations include two weeks of menus and recipes, which is alright - but I think a more practical approach is to give readers a more detailed analysis of foods they should or should not eat, and explain why. For example, Dr. Atkins (whatever else you think of him) lists foods according to whether they should be consumed frequently, moderately, or rarely. A person can then plan their own menus without trying to follow a cookbook. You may not have, for example, easy access year around to fresh bunches of watercress and arugula, or edamame. (In fairness, most of the ingredients in Dr. Cooke's recipes are commonly available). I would prefer to consult a list of many foods and see whether consuming one was likely to be of benefit or was likely to be harmful. I could then take the foods that are available, or most appealing, to me and plan my consumption accordingly. If you haven't already purchased other books which explain the advantages of a Mediterranean diet, exercise, weight loss, good and bad fats, and supplements like l-arginine and fish oil, then this book will provide information you may find revealing and helpful. The information about the role of the endothelium and nitric oxide will also be interesting to anybody dealing with heart disease and other problems related to a diseased endothelium (such as erectile dysfunction). And who knows, maybe you will be "cured".

Dr. Cooke is the world's number one expert on the nutritional supplement l-arginine and its antagonist, asymetric dimethylarginine. It's a mouthful, but among the keys to cardiovascular health. Dr. Cooke speaks with the authority of someone who has performed a huge amount of the "bench" research himself. If you're interested in knowing about the most powerful tools available to prevent heart attack and control cardiovascular risk, Dr. Cooke's book is a crucial addition to your library.

As a practicing cardiologist who aims to achieve shrinkage of coronary plaque in patients, we've applied Dr. Cooke's concepts with great success.

William Davis, MD author of Track Your Plaque

This is an excellent book on the workings of the heart.
It explains how a healthy endotheliam releases its own nitro.
Small amounts of L-arginine potentiate nitric oxide. This process
increases blood flow and reverses heart disease. The nitric
oxide relaxes blood vessels and facilitates blood flow.
The endothelium is known to potentiate the increase in blood
flow. This book will help to formulate an optimal strategy
to deal with impediments to blood flow and nutritional issues
which are at the periphery of heart health issues. It would be
an excellent addition to the medicinal personal health library.

My sister bought me this book, right after I had some heart palpitations and was admitted to a hospital. I read the book THREE times! Dr. Cooke verifies what I already know and believe and gave me many more additional insights as well.

But does it work? I applied Dr. Cooke's principles and after only six weeks I saw major results, confirmed by my cardiologist, as well as with blood tests.

Needless to say I bought 15 copies of the book and gave one to each of my family as presents. I will also buy more for my best friends.

This book truly saved my life.

It is not often that a Doctor writes so honestly. I love the recommendation to utilize diet and medication before resorting to invasive treatment.
Dr. Cooke has researched a timely and relevant field. He has the good sense to enlist assistance in articulating his research to the public in such an honest and straightforward manner.
He is a credit to his field of "The Youngest Science" as Dr. Lewis Thomas called it.