This book is a wonderful tool for Medical Immunology. My second year course at medical school runs only two weeks and there are so many informations and so many concepts to digest. At the beginning I was very skeptical about buying the book because its a very new book( first and only edition, from 2006) and there is no written review as I am the first person to writte this review on Amazon. It first start by discussing every necessary information to understand each concept then it move over to talk about clinical cases related to each concept. It also go to the very bottom of each condition and speculate concisely on the informations necessary we need to understand. For exemple ADA deficiency is a subtype of the wide range of SCIDs and in our notes there are no much infos about ADA and you really need to go back to the biochem notes to clearly understand the mechanism of ADA which will be very hard to do w/in two weeks. And the authors clearly break down the facts about ADA by stating on page 10 w/in a very short paragraph that "..ADA is required for purines metabolism and which is more active in lymphocytes, particularly T lymphocytes. In the absence of this enzyme, toxic metabolites accumulate and inhibit DNA synthesis so proliferation does not occur in response to polyclonal activators". They first save me a trip to last year biochem notes which are accross my table on the living room then, they break down why exactly ADA deficiency inhibit polyclonal activation. Great book I would recommend to any medical student for the Immuno class.