I had a hysterectomy 14 years ago and I have been studing natural alternative and Bio-identical hormone replacement for years. This book is great info for women considering NRT - Natural Hormone Treatment for peri-menopause and menopausal symtoms and for staying young and healthy.

Uzi Reiss and Elizabeth Vliet provide more thorough discussions of this topic, but Jonathan Wright has written magazine articles for years and offers a concise review of the evidence for bio-identical hormone replacement. Wright focuses on bio-identical hormone replacement, resulting in a briefer discussion, since he spends less time discussing studies of horse estrogens and artificial progestins.



Misleading, sensationalized media coverage of large, poorly designed, ethically questionable estrogen replacement studies, including the Womens Health Initiative and Nurses Health Study continues to discourage women from obtaining safe effective natural hormone replacement. These large studies of thousands of women used the same dose of Premarin horse estrogens for study subjects, without regard to symptoms. Doseage was not adjusted for individual study patients. I doubt anyone would volunteer for a thyroid hormone replacement study, if they were informed individual hormone levels would not be measured and everyone would receive the same hormone dose, irregardless of whether they exhibited hypothyroidism symptoms. What is surprising about the large overpublicized Premarin/Progestin studies is that women were willing to submit themselves to these dangerous, poorly designed studies and that the media has succeeded so thoroughly, in misleading the public.



Wright provides excellent information on the estrone/estradiol and estriol ratio correlation with cancer. He also explains studies indicating bio-identical progesterone decreases cancer.



Wright explains why animal lovers will want horse estrogen (Premarin) removed from the market, when they learn how inhumanely horses are treated to obtain it. Your HMO prefers dangerous horse estrogens, because they are less expensive to produce.



Physicians treat individual patients, not study groups. When safe bioidentical hormone replacement dose is adjusted to the individual patient, using repeated testing and gradual dose increases, dramatic improvements in depression,insomnia, anxiety, fatigue, interstitial cystitis, fibromyalgia and migraine often occur.



Florida Detox has been able to obtain all of these improvements, often in days, using bio-identical hormone replacement. These bio-identical hormones are sometimes almost the only medications, which highy allergic patients do not have adverse reactions to.



Steven Sponaugle

Research Director, Florida Detox

Uzi Reiss and Elizabeth Vliet provide more thorough discussions of this topic, but Jonathan Wright has written magazine articles for years and offers a concise review of the evidence for bio-identical hormone replacement. Wright focuses on bio-identical hormone replacement, resulting in a briefer discussion, since he spends less time discussing studies of horse estrogens and artificial progestins.

Misleading, sensationalized media coverage of large, poorly designed, ethically questionable estrogen replacement studies, including the Womens Health Initiative and Nurses Health Study continues to discourage women from obtaining safe effective natural hormone replacement. These large studies of thousands of women used the same dose of Premarin horse estrogens for study subjects, without regard to symptoms. Doseage was not adjusted for individual study patients. I doubt anyone would volunteer for a thyroid hormone replacement study, if they were informed individual hormone levels would not be measured and everyone would receive the same hormone dose, irregardless of whether they exhibited hypothyroidism symptoms. What is surprising about the large overpublicized Premarin/Progestin studies is that women were willing to submit themselves to these dangerous, poorly designed studies and that the media has succeeded so thoroughly, in misleading the public.

Wright provides excellent information on the estrone/estradiol and estriol ratio correlation with cancer. He also explains studies indicating bio-identical progesterone decreases cancer.

Wright explains why animal lovers will want horse estrogen (Premarin) removed from the market, when they learn how inhumanely horses are treated to obtain it. Your HMO prefers dangerous horse estrogens, because they are less expensive to produce.

Physicians treat individual patients, not study groups. When safe bioidentical hormone replacement dose is adjusted to the individual patient, using repeated testing and gradual dose increases, dramatic improvements in depression,insomnia, anxiety, fatigue, interstitial cystitis, fibromyalgia and migraine often occur.

Florida Detox has been able to obtain all of these improvements, often in days, using bio-identical hormone replacement. These bio-identical hormones are sometimes almost the only medications, which highly allergic patients do not have adverse reactions to.

Steven Sponaugle
Research Director, Florida Detox

Natural Hormone Replacement is a succinct, concise, surprisingly thorough explanation of the evidence supporting bioidentical female hormone replacement. Lengthier treatments of this topic devote more discussion to inadequately designed, overpublicized studies, including the Womens Health Initiative and US Nurses Health Study. Jonathan Wright focuses primarily on better designed studies, which received less publicity in over sensationalized media coverage. The discussion of estriol / estradiol plus estrone ratio and breast cancer rates is especially informative. Surprisingly, etiocholanolone testing is discussed in this unexpectedly thorough book. Increased cancer rates occurring with progesterone deficiency are clearly explained. Wright provides a rational analysis and overview of the relative risk of underemphasized cardiovascular mortality compared to overemphasized breast cancer risk.

Wright has written magazine articles for years and his ability to clearly explain large amounts of information and research concisely are refreshing.

We have seen bioidentical estradiol, progesterone, DHEA and testosterone replacement treat severe depression, anxiety, fatigue, insomnia, interstitial cystitis and migraine pain, at Florida Detox. Hormone replacement works much faster, than antidepressant therapy and can be used with patients who have adverse reactions, to almost every non-bioidentical pharmaceutical.

Steven Sponaugle, Research Director, Florida Detox

Natural Hormone Replacement is a succinct, concise, surprisingly thorough explanation of the evidence supporting bioidentical female hormone replacement. Lengthier treatments of this topic devote more discussion to inadequately designed, overpublicized studies, including the Womens Health Initiative and US Nurses Health Study. Jonathan Wright focuses primarily on better designed studies, which received less publicity in over sensationalized media coverage. The discussion of estriol / estradiol plus estrone ratio and breast cancer rates is especially informative. Surprisingly, etiocholanolone testing is discussed in this unexpectedly thorough book. Increased cancer rates occurring with progesterone deficiency are clearly explained. Wright provides a rational analysis and overview of the relative risk of underemphasized cardiovascular mortality compared to overemphasized breast cancer risk. Wright has written magazine articles for years and his ability to clearly explain large amounts of information and research concisely are refreshing. We have seen bioidentical estradiol, progesterone, DHEA and testosterone replacement treat severe depression, anxiety, fatigue, insomnia and migraine pain, at Florida Detox. Hormone replacement works much faster, than antidepressant therapy and can be used with patients who have adverse reactions, to almost every non-bioidentical pharmaceutical.

Steven Sponaugle, Research Director, Florida Detox

Read this book. It will get you long on knowledge you really should know in short order. A HUGE misunderstanding has been created (on purpose, by the major pharmaceutical companies, or through the unfortunate ignorance of medical professionals) about synthetic, altered, equine, patented, profitable hormone replacement therapy (HRT) vs. Bio-Identical HRT. Everybody should know the difference and how it can affect their health.

Bio-identical hormones are not all they are cracked up to be. They have serious, dangerous impacts on the human body. Please, if you are going to try these, do your homework first. A growing number of women are experiencing lethal side effects. Some don't make it out the other side. I am one of the lucky ones - I survived the blood clots in my legs and two near-fatal, year-long illnesses connected with use of "natural" progesterone. Since that time, I have been contacted by scores of women who have suffered due to use of these hormones. I hope this information will be helpful to someone else, too. Please, safeguard your health - no one else is going to do it for you.

This MAN does not understand estrogen at all. It is sad that so many women are apparently putting their health into his hands. The reason why so many women and good clinicians are avoiding products like Tri-est is because these products don't feed our bodies the necessary estrogens that our bodies actually produce from our ovaries. Giving women estriol and estrone just blocks our receptors from receiving the necessary and most important E2-estradiol. Our bodies will then metabolize the E2 into the others naturally. Research supports this aspect clearly. The other thing about this guy and his book is that he bounces everything he says off of premarin studies and does not keep the information flow consistent one way or another.

Most women getting on bio-identical hormones these days have never used premarin and want good research or clinical comparatives to support their choices with regards to bio-identicals. This book does not provide either good knowledge or research. Additionally, this book is quite disappointing for one that Amazon places so highly in their search engine.

Instead, I would recommend Wiley's book for the radical approach to understanding what it is we actually want to achieve with our bio-identicals, and Reiss's book for good information on how to monitor ourselves when using bio-identicals. However, Reiss, (another boy doctor) is also a proponent of Tri-est, probably because its just easier for him to prescribe.

Once our female clinicians have really worked out the bio-identicals that are working well for us, then we will all have great data to support our choices. In the meantime, avoid this book.

This MAN does not understand estrogen at all. It is sad that so many women are apparently putting their health into his hands. The reason why so many women and good clinicians are avoiding products like Tri-est is because these products don't feed our bodies the necessary estrogens that our bodies actually produce from our ovaries. Giving women estriol and estrone just blocks our receptors from receiving the necessary and most important E2-estradiol. Our bodies will then metabolize the E2 into the others naturally. Research supports this aspect clearly. The other thing about this guy and his book is that he bounces everything he says off of premarin studies and does not keep the information flow consistent one way or another.

Most women getting on bio-identical hormones these days have never used premarin and want good research or clinical comparatives to support their choices with regards to bio-identicals. This book does not provide either good knowledge or research. Additionally, this book is quite disappointing for one that Amazon places so highly in their search engine.

Instead, I would recommend Wiley's book for the radical approach to understanding what it is we actually want to achieve with our bio-identicals, and Reiss's book for good information on how to monitor ourselves when using bio-identicals. However, Reiss, (another boy doctor) is also a proponent of Tri-est, probably because its just easier for him to prescribe.

Once our female clinicians have really worked out the bio-identicals that are working well for us, then we will all have great data to support our choices. In the meantime, avoid this book.

As both a female and one over 45 who is in the menopausal phase of her life, this book is incredibly helpful because it gives one an alternate view, very different from what AMA and FDA guidelines stipulate. We are in control of our bodies and can ultimately make our own decisions, but only with enough subjective information to go by. Many physicians may not be open to natural hormone replacement, but there are many who are. Women just need to read this book, among others, to become better educated about their choices regarding controlled substances being ingested into the body.

I feel this book hurts the message that using alternatives to traditional medicine should be explored. This is one of many examples throughtout the book. On page 22 "In real numbers, this means that for every 1,000 women using one of these drugs, 300 will eventually develop breast cancer from the HRT itself." This sounds very scary but is flat out wrong. A 30% increase in risk is not a 30% risk as this book implies. In real numbers this means that instead of 100 women out of 1000 developing breast cancer 130 women out of 1000 would develop breast cancer on HRT. Not to mention that a lot of studies do not show such a high increase in risk. How can anyone trust the assertions of this book if in the first 22 pages there are such blatant untruths.

As a practicing pharmacist, it upsets me that such basic knowledge of hormones was not taught in school. Doctors aren't even taught some of the basic information Dr. Wright discusses in this book. I wish all women would read this book and I wish all doctors would open their minds to the information presented in it. For all the thousands of women I know to be using natural hormone replacement therapy, I don't know a single "unhappy customer".

Like many women, I thought the only way to deal with perimenopause and menopause was with Premarin [made with pregnant horse estrogen, Yuck] and other hormones pushed by large pharmecuetical companies. This book was a real eye opener for me. It explains how the estrogens naturally found in a woman's body can't be patented, because they are just natural bodily hormones. Therefore, the drug giants who court all the doctors have no financial incentive to tout naturally occurring hormones. Instead, they push the horse estrogens, and other unnatural products, which cause side effects.

This book explains how a woman with a good doctor can get a pharmacy to mix a custom-blended natural hormone replacement with few, if any, side effects, because it's what's in your body already.

I took this book to my doctor who said of course he'd be happy to prescribe natural hormones as suggested in the book. Had I not brought it up, I, too would have been prescribed that horrible Premarin or Prempro, made from the urine of pregnant [and abused] mares.

I've spoken with other women over 45-50 who take the horse estrogen, Premarin [the name comes from PREgnant MARe's urINe], and they were shocked that there was an alternative their doctors had never bothered mentioning.

Anyone interested in natural health should buy this must-read, and then discuss with your doctor.

Don't let the size of this wonderful book, fool you. It's filled with life changing help for the maturing woman. The Whys & Hows of Natural "vs" Patented Hormone Replacement Drugs.... plenty of information on the "forgotten" hormone needs also. This book lets us KNOW the effect of Hormones on Cancer, Senility, Heart disease, Osteoporsis. Explains in clear detail, with resources. Advice on herbs & foods that make this transistion easier. EXCELLENT!

This is a light, quick read, but has a great deal of information you'll have trouble learning elsewhere. Did you know that there are three kinds of Estrogen? That's just for starters. I suffered from depression and fatigue after a hysterectomy, and months of research took me to this book, a new doctor, a new prescription for "natural" hormones, and I'm a new woman, or really I got my old self back, thank God and the authors. Plus, because of this book, I am practically an expert, and I've taken control of my own health care.

I am 50 years old. Due to high dose steriods used during chemotherapy, I suffered significant bone loss. Also, I am experiencing High BP and High Cholesteral as well as other menopausal symptoms. Hormone Therapy is essential to maintaining a healthy cardiovascular system and bone density. Because my breast cancer was estrogen positive..I wanted a safer treatment than Premarin...This book explains the big picture and gives hope for a safe alternative to conventional hormone therapy for living longer and having a higher quality of that extended life.

Natural Hormones

Natural Hormone replacement is a MUST read for any woman who is looking for natural alternatvies. I Found this book interesting and VERY Helpful.

I had a hysterectomy 5 years ago and have been very sick ever since but was diagnosed with Chronic Fatigue Syndrome, Depression and Panic Disorder. It started within a week of the surgery. (symptoms were mild at first but progressively got worse until I was bedridden. I have been declared disabled by a Social Security Disability judge. I have tried various conventional Estrogen Replacement Therapies but without much help . (pills, creams, shots, patches have caused all sorts of reactions - even borderline delirium and total incapacitation. A friend told me about this book and I immediately found an innovative GYN who worked with a compounding pharmacist who cautiously (with slow increases) prescribed this Natural Hormone Therapy for me via a cream since I don't absorb by mouth. Within one month, I began to notice a difference. I am now feeling wonderful for the first time in years - pre-hysterectomy normal. I am so thrilled that I am telling my story to all that will listen. I have friends that have seen such a dramatic change in me that they are buying the book and changing doctors to get off of the unnatural estrogen derived from horse urine they are on. This book is a must reading for all women and doctors who treat them. This information must get out -- had I known, perhaps my 5 year nightmare would have been avoided.