While new insights into the mechanisms and the treatment of stroke have been obtained from animal experiments over the past several years, this is the first book in more than two decades to compile research in this essential area. Calling on a group of cutting-edge researchers, it offers detailed explanations of the methods and techniques for accomplishing different stroke models in rats. As of now, no specific neuroprotective treatment for ischemic stroke is available. This book provides a starting point for those researchers employing stroke models to develop new drugs to counteract this problem.